talquetamab will boost the stage or result of ergotamine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. Talquetamab brings about cytokine launch syndrome (CRS) that may suppress activity of CYP enzymes, causing increased publicity of CYP substrates.
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istradefylline will improve the degree or influence of ergotamine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
itraconazole will enhance the level or impact of ergotamine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Improved risk of ergotism bringing about cerebral ischemia and/or ischemia on the extremities
caffeine will boost the stage or effect of fezolinetant by impacting hepatic enzyme CYP1A2 metabolism. Contraindicated. Fezolinetant AUC and peak plasma concentration are amplified if coadministered with medicines that happen to be weak, average, or strong CYP1A2 inhibitors
griseofulvin will decrease the extent or result of ergotamine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
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